報告題目：Pushing the Limits of Coordination-Driven Self-Assembly: Construction of Giant 2D and 3D Supramolecular Architectures
報告人：Prof. Xiaopeng Li (李霄鵬教授)
University of South Florida
報告時間：2019年12月4日（周三）下午3:00-5:00
報告地點：化學樓一號會議室
邀請人：朱錦濤 教授
報告人簡介
李霄鵬教授2004 年于鄭州大學化學系獲本科學位，2008 年在美國克利夫蘭州立大化學系獲博士學位。2009 起在阿克倫大學從事博士后研究。2012 年在德州州立大學任化學系助理教授，開展獨立工作。2016 年至今在南佛羅里達大學先后任助理教授、副教授。主要研究興趣集中用超分子化學以及質譜表征技術。曾獲得多個獎項，包括超分子領域著名的Cram Lehn Pedersen Prize(2019)、英國皇家化學會Fellow (FRSC, 2017)、中美華人化學與化學生物學教授協會杰出青年教授獎(CAPA，2017)、德州州立大學杰出學術成就獎(2016)、美國Research Corporation 基金會 Cottrell 學者獎 (2015)。共發表150 余篇論文，文章總引用次數超過5000 次，H-index 42。
報告摘要
Due to its highly directional and predictable feature, coordination-driven self-assembly has evolved into a well-established methodology for constructing 2D and 3D supramolecules. Up to date, this field has matured in the context of a large variety of macrocycles and polyhedra, which however, still suffered from a lack of complexity and thus were unable to reach the high degrees of functionality found in natural systems. With the goal of assembling structures with high complexity, we pushed the limits of coordination self-assembly through constructing a series of giant 2D and 3D supramolecular architectures. First, multi-armed building blocks were synthesized using pyrylium and pyridinium salts chemistry for the self-assembly of 2D nested concentric hexagons, or Kandinsky circles, which showed high antimicrobial activity. Second, step-wise strategy was utilized to combine folding and self-assembly together to construct fuzzy supramolecular hexagonal grids (diameter > 20 nm, MW > 65 kDa) with intrinsically ordered and disordered domains. Third, pre-assembled supramolecular polyhedra with precisely-controlled shapes and sizes could further assemble into double-helical nanowires with a non-natural parastichy pattern. In conclusion, through further understanding of self-assembly of supramolecules, our research could advance the design, research and development of new synthetic materials with molecular level precision.
